The Virtual Hospital

ElectricPE: The Diagnosis of Pulmonary Embolism: Case Study 14

History of Previous Emboli

Jeffrey R. Galvin, M.D. and James J. Choi, B.S.
Peer Review Status: Internally Reviewed


Case #14 is a 57 year old male farmer , non-smoker, with progressive dyspnea on exertion who presented to this hospital for a second opinion. He had a long history of varicose veins treated in the past with superficial vein stripping.

He felt well until 1 year age when he developed an acute episode of shortness of breath one morning. He was assessed by his local physician the same day. He could find nothing significantly wrong and was sent home on anti-inflammatory medication. He was hospitalized one week later because of persistent complaints of dyspnea on exertion.

A perfusion scan done at that time was read as high probability. There are numerous segmental and subsegmental perfusion defect. A ventilation scan was not done. He was anticoagulated and sent home.

He presented to this hospital after one year of chronic shortness of breath for a reassessment. A cardiac echo showed evidence of pulmonary hypertension with an enlarged right ventricle and right atrium. Bilateral venography was normal.

His pulmonary function showed normal spirometry with a diffusing capacity that was reduced (75%) of predicted His chest x-ray revealed mild cardiomegally with enlarged central pulmonary arteries. The chest radiograph suggested pulmonary artery hypertension. A repeat perfusion scan, done at the time of the current admission, showed numerous segmental and subsegmental perfusion defects that were unchanged from the scan done one year prior. The ventilation scan was normal. The diagnosis at that time was findings of pulmonary emboli, unchanged from one year ago. No evidence of acute emboli.

Despite the above V/Q scan reading an angiogram was requested. The angiogram showed multiple vessels with smooth narrowing consistent with old emboli. No new clots were identified.

Case Assessment
This is a 57 year old farmer who presented with a past history of varicose veins, acute shortness of breath followed by chronic dyspnea for one year, pulmonary hypertension, high probability perfusion scans that were unchanged over 1 year, and angiographic evidence of old clots.

1. Sequential perfusion scans can be quite helpful when assessing new or persistent symptoms related to pulmonary emboli.

2 . A single High probability ventilation/perfusion scan may not be a reliable indicator of acute emboli when the patient has a history of prior emboli. (REFERENCE)

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