The Virtual Hospital

ElectricPE: The Diagnosis of Pulmonary Embolism: Case Study 2

Non-specific Symptoms

Jeffrey R. Galvin, M.D. and James J. Choi, B.S.
Peer Review Status: Internally Reviewed


This case presented to the hospital complaining of 4 months of chronic fatigue, dyspnea and dull chest pain on exertion. He also complained of intermittent wheezing and carried the diagnosis of adult onset asthma. He was admitted for a coronary angiogram which was normal. An examination of the upper gastrointestinal tract with barium revealed mild gastroesphogeal reflux.

The cardiac silhouette and pulmonary vasculature were both normal. He was noted to have bilateral pleural thickening that was obtained 6 months earlier. There was however, an area of abnormal increased density which was noted in the lingula.

There is a segmental size perfusion defect in the area of the lingula that corresponds to the abnormality on the chest x-ray. Several smaller perfusion defects are noted in the periphery of both lungs.

There are multiple small areas of ventilation abnormality that are present in both lung bases.

Ventilation/Perfusion scan reading:
This scan was called indeterminate because of the lingualar perfusion defect that matched the chest x-ray abnormality.

A Left PA pulmonary angiogram revealed a possible clot in a lower lung field artery.

A selective angiogram of the area in question revealed a filling defect within a lingular pulmonary artery.

Case assessment
This is a 58 year old man who presents with chronic exertional chest pain, shortness of breath and wheezing.

The clinical presentation of pulmonary embolus may be misleading because the symptoms are often non-specific.

Over a three month period this gentleman was given the diagnosis of coronary artery disease, asthma and esophageal disease. The possibility of pulmonary embolus was not considered until it was suggested on the chest radiograph.

Cardiac catheterization must be performed properly in order to be a reasonably sensitive test.

In order to effectively rule out the presence of a clot the guidance of the perfusion scan is quite important. The angiographer should make use of this information to help decide which vessel should be catherized and what radiographic projection should be used. It is often necessary to obtain multiple projections and subselective, magnified view.

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